ARG L-Ornithine-L-Aspartate x 100g

Delivery 7 - 14 days

What It Does

L-Ornithine-L-Aspartate (LOLA) supports healthy nitrogen metabolism by promoting the natural detoxification of ammonia through the urea cycle and glutamine synthesis pathways. By providing key amino acids, LOLA helps maintain liver function, ammonia clearance, and metabolic balance, especially during times of increased nitrogen stress. Each serving delivers 3 grams of clinically relevant LOLA in a versatile powdered form.

L-Ornithine-L-Aspartate (LOLA) supports healthy nitrogen metabolism by promoting the natural detoxification of ammonia through the urea cycle and glutamine synthesis pathways. This clinically relevant formula helps maintain liver function, ammonia clearance, and overall metabolic balance, particularly during periods of increased nitrogen stress.

L-Ornithine activates carbamoyl phosphate synthetase, the rate-limiting enzyme of the urea cycle, enhancing the conversion of ammonia to urea in periportal hepatocytes for excretion.

• L-Aspartate serves as a substrate in transamination reactions and contributes to glutamine synthesis, aiding in ammonia removal via non-urea pathways.

• Glutamine Synthetase Activation in perivenous hepatocytes, skeletal muscle, and brain tissue facilitates an additional mechanism for reducing circulating ammonia.

• Clinical Research supports the use of oral LOLA in improving ammonia metabolism and mental state, especially in individuals with hepatic metabolic burden.

• Meta-Analysis Findings indicate that LOLA supplementation significantly supports detoxification pathways.

Ingredients