5-HTP is a direct precursor to serotonin and is taken among other things to improve mood, as a treatment for anxiety, and beneficial in weight loss.
5-HTP is derived from the seeds of the Griffonia Simplicifolia, a West African medicinal plant.
In addition to the treatment of depression, scientific studies from around the world have shown 5-HTP to be effective in:
Relieving symptoms of Seasonal Affective Disorder
Relief From and Prevention of Migraine Headaches
Reduction of the rate of Heart Disease as a result of Lowering Anxiety and Depression.
How 5-HTP works in relation to L-Tryptophan, St. John's Wort and SSRIs like PROZAC.
5-HTP (5-hydroxytryptophan) works by increasing the cell’s output of serotonin.
L-Tryptophan must be converted to 5-HTP before it can then be converted into serotonin. 5-HTP may cause gastrointestinal problems for a small percentage of users but if you are not in that category, 5-HTP is the fastest and most effective supplement for increasing your serotonin levels.
St. John’s Wort works like SSRIs in that it increases the availability of serotonin in synapses (junctions between neurons) by blocking their reuptake but also increases the availability of norepinephrine, which increases energy, alertness, and dopamine levels providing a feeling of well-being.
SSRIs (selective serotonin reuptake inhibitors) are the class of prescription drugs including PROZAC. SSRIs work by increasing the availability of serotonin in synapses (junctions between neurons) by blocking their reuptake.
5-HTP vs. SSRIs
A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan (5-HTP) and fluvoxamine. Psychopathology. 1991,24:53-81
Dr. W. Poldinger of the Psychiatrische Universitatsklinik in Basel, Switzerland in a double blind, multi-center controlled study using patients diagnosed with depression found that after week 6, both the patients taking 100 mg 5-HTP 3 times per day and those taking 150 mg fluvoxamine (an SSRI) 3 times per day, had equal numbers showing about 50% improvement but with 5-HTP proving to be better tolerated than the SSRI and having about an 11% lower failure rate than the SSRI group.
5-HTP is the direct precursor to serotonin
According to University of Mississippi researcher Ronald F. Bore, Ph.D., in his article: Serotonin: The Neurotransmitter for the 90’s. Drug Topics. 1994, serotonin is "The Neurotransmitter of the 90s’" "Of the chemical neurotransmitter substances, serotonin is perhaps the most implicated in the etiology or treatment of various disorders, particularly those of the central nervous system including anxiety, depression, obsessive-compulsive disorder, schizophrenia, stroke, obesity, pain, hypertension, vascular disorders, migraine, and nausea."
- Supplement Facts
Serving Size 1 Capsule
Servings Per Container 90